An anal fissure is a tear in the lining of the lower rectum anal canal that causes pain during bowel movements. Anal fissures don't lead to more serious problems. Most anal fissures heal with home treatment after a few days or weeks. These are called short-term acute anal fissures.
% nitroglycerin ointment : in the treatment of chronic anal fissure pain.
Medically reviewed by Drugs. Nitroglycerin is a nitrate that dilates widens blood vessels. Nitroglycerin rectal is used to treat moderate to severe pain caused by chronic anal fissures tears in the skin lining your rectum. You should not use nitroglycerin rectal if you have: severe anemia a lack of red blood cells , or a brain injury , hemorrhage, or tumor. You also should not use nitroglycerin if you are using medicine to treat pulmonary arterial hypertension PAH , such as riociguat, Adempas , sildenafil Revatio , or tadalafil Adcirca. Do not take erectile dysfunction medicine Viagra, Cialis, and others while you are using nitroglycerin rectal , or you could have a sudden and serious decrease in blood pressure.
Anal Fissures: A Real Pain. Patients with anal fissures frequently seek care for pain. Anal fissures also called fissure in ano are a common affliction— second only to hemorrhoids in terms of patient complaints about the anus. However, researchers have been unable to estimate the true incidence of anal fissures.
Application of a 0. You rub a pea-sized dot of cream on the fissure twice a day. It is a good idea to either wear gloves when applying the nitroglycerin cream or wash your hands right after. The skin on your fingers can absorb the medicine and increase your chance of side effects.